The mixed nine and under quartet of Niall Goy, Lucy Gratton, Matt Lamkin and Isabella Munro won the freestyle and mixed stroke relays.
Luke Higginbottom won the 11-year-old boys 50 metre butterfly, while Charlie Humphries, 13, picked up a quartet of victories in the 100 freestyle, breastroke, backstroke and individual medley races.
There was also a host of second place finishes, Owen Smith and Matt Watkinson in the backstroke, Lucy Gratton in the breastroke, Holly Anderson in the freestyle and nutterfly, Lucy Ambrose in the butterfly and freestyle, Lorna Milligan in the individual medley, and C.J Smith in the breastroke and freestyle.
On the night Worksop also had a number of swimmers achieving personal best times, and some went up against competitors in older age groups – most notably 12-year-olds Josh Thrower and Nathan Pogson in the under 15 category.
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The overall result was a close run thing with Worksop finishing third behind Sherwood and CABSC, setting up a thrilling final round on Saturday.
Worksop are currently fourth in the league, two points behind their Bassetlaw rivals Retford.