The Tigers progressed into this round after a thrilling 4-4 draw against Ramsbottom United, which saw Worksop progress on penalties.
St Neots Town play in the Southern League Central Division and currently sit eighth in the table after two wins and four draws from their opening seven league fixtures.
The Saints come into this fixture on the back of a 4-1 victory over Biggleswade on Tuesday night and they also won by the same result in the previous round of the FA Trophy, beating Bedworth Town on the road.
“They are an attacking side, and they’re at home, so they will want to be getting on the front foot on their home pitch and attack us,” said Rouse.
“We want to go there and fight fire with fire and I think we can do that.
“If you look at our side from two weeks ago, we lost to Sutton Coldfield and it felt like there was doom and gloom around the place and people were down in the dumps.
“Since then – which can feel like a long time in football – we went through in the FA Trophy against Ramsbottom, took a point away at Stamford and we won against Spalding at home and suddenly things have been lifted and for us, it is only one defeat in 12 90-minute games.
“You have got to change impressions in football and we only started in May with a new group and in a new environment and we are only going to get stronger.
“We have a couple of loan players, so we need to go to their parent clubs and see if they will allow us to use them in the FA Trophy game.
“Naturally in football, there are always changes, we would like to go there with a settled squad and a settled team to keep moving forward as a side.
“You want the big days and you want the big draws; we had one earlier on in the season against Chester.
“It was just a shame the crowds are limited because we would have had a big crowd in there.
“We want to bring big days here for this football club, and this is why we came here.”
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