The Audi A4 was allegedly stolen from the driveway of a property in Ipswich, in Suffolk, at 4.30am on Wednesday.
The vehicle was subsequently circulated as stolen and located by Nottinghamshire Police but failed to stop when requested to do so.
A short police pursuit then followed and at about 6.50am the suspect vehicle was involved in a collision with a fuel tanker, on the slip road at junction 30 of the M1 northbound in Derbyshire.
Two teenage boys from Ipswich, aged 14 and 17, and a 14-year-old boy from Thetford, in Norfolk, have been arrested on suspicion of burglary and other offences. They have been released under investigation pending further inquires.
Three other teenage boys, aged 15, 16 and 17, are currently in hospital in Sheffield for treatment to serious injuries, which are not life-threatening. They will be questioned by police at a later date.