Flybe flight BE263 departed from Edinburgh this morning at 9.58am.
The flight declared an emergency and has landed at Manchester airport.
A Flybe spokeswoman said: "Flybe can confirm that the above flight has diverted to Manchester Airport this morning due to a passenger-related medical emergency on board.
"The airline would apologise to the remaining passengers for any inconvenience experienced as a result of this temporary disruption to their travel."