The section of the M1 near Nottingham will close between 9pm on Saturday, June 16 until 6am on Sunday, June 17.
Highways England has said the closure is for a “gantry installation”.
The works are part of Highways England’s project to to convert the M1 into a smart motorway between junctions 23a to 25 which began in March 2017.
Highways England has advised people to plan ahead and allow extra time for journeys.